Malignant Gastrointestinal Neuroectodermal Tumor: A Case Report and Literary Review for a Rare Differential Diagnosis

Malignant gastrointestinal neuroectodermal tumor (GNET) is an infrequent soft-tissue sarcoma, formerly referred to as clear-cell sarcoma-like (CCSLGT) and frequently reported in the literature sarcoma of tract (CCS-GI); it characterized by absence melanocytic differentiation presence nontumoral osteoclast-like giant cells (OLGCs). The current study reports a case 79 year old woman admitted emergency department (ED) with symptoms constipation intestinal obstruction; mass was found within ileal wall necessitating surgical approach. Immunohistochemically, surprisingly had hallmark GNETs. Unfamiliarity tumors features GNETs can easily lead misdiagnosis pathologist. Therefore, comprehensive evaluation, including morphology additional studies, required for appropriated diagnosis. Furthermore, without high index suspicion, there actually no consensus on staging or treatment.